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Scientists have finally found out why MPA medroxyprogesterone, otherwise known as Provera performs just as well in low doses in small children who are dealing with early sex traits, as it does for women in high doses with breast cancer. You may have heard of Prov ....

Middle of Essay
.... the release of GnRH. Since these children are still producing steroids without GnRH being released, low doses of Provera are not effective. For the body to produce steroid hormones it must convert cholesterol into estrogens and other related substances. In order for this process to take place, several steps are involved which are controlled by a certain enzyme. In knowing this, Lee wanted to find out if blocking the action of an enzyme would be reached with high doses of Provera. What Lee and Auchus found out was that Provera could inhibit certain enzymes, (3HSDII) which influence hormone production, that low doses of Provera could disrupt ....