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Depression is a psychiatric disorder characterized by feelings of worthlessness, guilt, sadness, helplessness, and hopelessness. It is different then normal sadness or grief from the loss of a loved one because it is persistent and severe. Clinical depression has ....

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.... by alternating depressed and manic episodes. This is an actual brain disfunction. In the major depression or the depressed phase of bipolar illness, a depressed mood predominates, even though the patient may not be aware of feeling sad. Typically, he or she loses all interest in activities. Symptoms include sleep disturbances, not able to concentrate or to make decisions, loss of appetite or greatly increased appetite, slowed thinking and decreased energy feelings of worthlessness, guilt, hopelessness, diminished sexual interest, and recurrent thoughts of suicide and death, sometimes leading a person to actually committing suicide. In the manic pha ....