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In Shakespeare’s Macbeth, Macbeth and Lady Macbeth both show signs of what would today be diagnosed as symptoms of schizophrenia. Schizophrenia is defined as "a psychotic disorder characterized by loss of contact with the environment, by noticeable deterioration ....

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.... are strung together in an incoherent way. Lastly, some schizophrenics withdraw emotionally, for example, their outlook on life is deadened and they show little or no warmth, and also physically, such as their movements become jerky and robot-like. What causes people to become schizophrenic? One possibility, in Macbeth and his wife’s case is guilt. Macbeth, in trying to become king, kills some people he knew very well and was loyal to at one time. He really did not want to have to Banquo, but he felt he had to so that he could become king. He said to his wife, "We will proceed no further in this business: He hath honored me of late." (I.7.31-32) Lad ....